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于乐祥，博士，中国科学院昆明动物研究所研究员。2019年毕业于中国科学院生物物理所，获得理学博士学位，同年起于约翰霍普金斯大学、哥伦比亚大学从事博士后研究，2025年加入昆明动物所，组建系统代谢生物学学科组担任PI。目前在Cell Metabolism（2023、2024、2025）, Science Advances, Biomaterial等杂志发表论文20余篇。

经历

2010年-2014年，山东农业大学，学士

2014年-2019年，中国科学院生物物理研究所，博士

2019年-2020年，约翰霍普金斯大学，博士后

2020年-2024年，哥伦比亚大学，博士后

2024年-2025年，哥伦比亚大学，副研究员

2025年-至今 ???中国科学院昆明动物研究所，研究员

近5年内发表的代表性论文/专著

1.??Yu L, Yang YX, Gong Z, Wan Q, Du Y, Zhou Q, Xiao Y, Zahr T, Wang Z, Yu Z, Yang K, Geng J, Fried s, Li J, Haeusler RA, Leong KW, Bai L, Sun L, Wang P, Zhu BT, Wang L^#, Qiang L^#. FcRn-dependent IgG Accumulation in Adipose Tissue Unmasks Obesity Pathophysiology.?Cell Metabolism. 2025, Doi.org/10.1016/j.cmet.2024.11.001.

2.??Yu L, Wan Q, Liu Q, Fan Y, Zhou Q, Skowronski A, Wang S, Shao Z, Liao C, Kennedy B, Ding L, Zha S, Que J, LeDuc C A, Sun L, Wang L^#, Qiang L^#. IgG is an aging factor that drives adipose tissue fibrosis and metabolic decline.?Cell Metabolism. 2024. Doi.org/10.1016/j.cmet.2024.01.015.Accompanied Commentaries in?Nature Aging,?Nature Reviews in Endocrinology?and?Science signaling

3.??Zhou Q^#,?Yu L^#, Cook JR, Qiang L^#, Sun L^#. Deciphering the decline of metabolic elasticity in aging and obesity.?Cell Metabolism. 2023 Aug 18; S1550-4131(23)00296-6. Highlighted and recommended in the?Cell Metabolism: DOI: 10.1016/j.cmet.2023.08.006 &?Nature Reviews Endocrinology: DOI: 10.1038/s41574-023-00914-4

4.??Yu L*, Gao Y, Aaron N, and Qiang L^#. A glimpse of the connection between PPARγ and macrophage.?Front. Pharmacol. 2023 14:1254317. doi: 10.3389/fphar.2023.1254317

5.??Yu L*. New Perspectives on Cancer Applicability of Falcon Systems Studies of Lipotoxicity.?J Mod Med Oncol, 2023; 3: 8. DOI: 10.53964/jmmo.2023008.

其他代表性论文/专著

1.??Yu L, Chen Y, Wei Y^#, He R^#. D-ribose is elevated in T1DM patients and can be involved in the onset of encephalopathy.?Aging?(Albany NY) 2019, 11(14):4943-4969.

2.??Chen Y*,?Yu L*, Wang Y, Wei Y, He R. D-Ribose is a major contributor to the glycation of serum protein.?Biochim Biophys Acta Mol Basis of Disease, 2019, DOI.org/10.1016/j.bbadis.2019.05.005.

3.??Kang N*,?Yu L*, Liu Y, He R. Changes in Ribose and Ribokinase in STZ-induced Type 2 Diabetic Rat.?Progress in Biochemistry and Biophysics, 2023, DOI.org/10.16476/j.pibb.2023.0150.

4.??Cao X*,?Yu L*, Wei Y, Qu M, He R. Changes in Ribose, AGEs and Transketolase in Female GK Rat, a Type 2 Diabetic Model.?Progress in Biochemistry and Biophysics, 2022, DOI.org/10.16476/j.pibb.2022.0161.

5.??Wu B *,?Yu L*, Hu P, Lu Y, Li J, Wei Y^#, He R^#. GRP78 protects CHO cells from ribosylation.??Biochim Biophys Acta Mol Cell Res, 2018, 1865(4):629-637.